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After the success of peptide agonists of GLP-1R (a class B G-protein coupled receptor) in the treatment of diabetes, drug discovery scientists saw the opportunity for small molecule agonists of GLP-1R
J Clin Invest (2008) 118(11):3693700.10.1172/JCI36461 28 WuTZhaoBRBoundMJChecklinHLBellonMLittleTJet alEffects of different sweet preloads on incretin hormone secretion, gastric emptying, and postprandial glycemia in healthy humans
Chronic treatment with a selective ligand for the sigma-1 receptor chaperone, SA4503, up-regulates BDNF protein levels in the rat hippocampus
CAT, GPx and Prx2 are essentially cytosolic enzymes
S., & Das, K
Waist circumference measures abdominal fat distribution
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